|
|
|
|
홍석철 ( Hong Suk-Chul ) - 강동성심병원 내과
권정혜 ( Kwon Jung-Hye ) - 한림대학교 의과대학 내과학교실
한수정 ( Han Su-Jung ) - 강동성심병원 완화의료병동
|
|
Abstract
|
|
|
|
|
|
Opioids are important drugs for the management of severe cancer pain without a ceiling effect. However, opioid administration leads to dose-limiting complications including drowsiness, hallucinations, delirium, respiratory depression, cognitive impairment, seizure, myoclonus, and hyperalgesia. Opioid-induced hyperalgesia (OIH) is a paradoxical phenomenon as opioid exposure increases pain sensitivity. Reducing or stopping opioids, opioid rotation, or co-administration of N-methyl-D-aspartate (NMDA) antagonists have been suggested for the management of OIH. In this study, we report two clinical cases of successful management of OIH in cancer pain patients that were treated with opioids.
|
|
|
KeyWords
|
|
Neoplasms, Pain, Opioid analgesics, Hyperalgesia
|
|
|
원문 및 링크아웃 정보
|
|
 
|
|
|
등재저널 정보
|
|
  
|
|
|
|
|